IUI
(Intrauterine Insemination)
IUI (Intrauterine Insemination) is a procedure for treating infertility. In the laboratory prepared Sperm is placed directly in the uterus in order to increase the likelihood of egg (oocyte) fertilization resulting in natural pregnancy.
In the Modern Reproductive Medicine Clinic Reprolife, the IUI method is widely used for the treatment of infertility.
Indications for intrauterine insemination: male factor
- mild deviation in sperm parameters (high seminal fluid viscosity (SFV) , hypospermia – decrease of semen volume, concentration, and mobility);
- the presence of antisperm antibodies (ASA);
- sperm cryopreservation (“sperm freezing”);
- ejaculatory dysfunction;
- conditions after chemotherapy and radiation therapy.
Indications for intrauterine insemination: female factor
- cervical abnormalities;
- disorders of ovulation amenable to medical treatment;
- the presence of antisperm antibodies (ASA);
- vaginismus.
- use of donor sperm.
IUI is performed after a preliminary examination of the couple.
Requirements to undergo intrauterine insemination (IUI)
- patency of at least one fallopian tube;
- minimum sperm concentration and motility of spermatozoa to mazimize probability of conception;
- presence of ovarian reserve (oocyte supply);
- woman’s age up to 35 years.
The Step-by-Step IUI:
Diagnostics
Fertilization by the intrauterine insemination method of IUI is carried out after a preliminary examination of the couple. A woman and a man undergo a special examination of reproductive health. Both partners also need to undergo general tests: determine the blood group and Rhesus factor, undergo testing to rule out sexually transmitted infections, HIV and hepatitis. The cost of the examination depends on the number and complexity of diagnostic methods.
Ovarian stimulation for ovulation induction
Duration of ovarian stimulation is 11-12 days. This stage is very important to increase the success of IUI. Medications induce simultaneous growth and maturation of 2 follicles with optimization of endometrium (mucous membrane of the uterine cavity) to prepare for further implantation of the embryo. During this period, ultrasound control (folliculometry) of treatment effectiveness. After follicles and endometrium have reached the desired size, an ovulation trigger is introduced (a medication that ensures final maturation of the egg (oocyte) – a process which takes 36 hours, following which the ovarian follicles rupture and release of oocytes.
Semen preparation
Semen preparation for IUI consists of processing semen in an embryological laboratory – separating immobile spermatozoa, abnormal sperm with head or tail defects. The aim of semen preparation is to improve the sperm quality and to yield as many normal motile spermatozoa as possible.
This procedure is done 2 hours before the intrauterine insemination.
Insemination
36 hours after induction of final maturation (trigger of oocyte release) prepared sperm is brought into the uterine cavity. This procedure is painless and does not require anesthesia. In our clinic, one program of insemination includes two-fold injection of sperm (first – before ovulation, at the day the trigger injection is done and 36 hours after – during ovulation) – this method increases the chances of pregnancy.
Support during implantation period before pregnancy and pregnancy test
After ovulation, support for the second phase of the menstrual cycle is prescribed to optimize the conditions for the embryo attachment to the uterine cavity under hormonal control: progesterone and estradiol. 12-14 days after ovulation blood test to confirm of your pregnancy is done.
Appointment for a consultation with a reproductive specialist
The private clinic Reprolife offers patients modern reproductive technologies at an affordable price. Doctors with many years of experience work with patients, who consider all the specifics of the couple’s health and select individual treatment programs. Our goal is to help every couple become happy parents of their own child.
If pregnancy does not occur for a long time, do not postpone a visit to a reproductive specialist. Take the first step towards parenthood today — make an appointment for consultation with a doctor in Kyiv by phone or use an online chat with the clinic manager.
Our specialists
chief medical officer, leading reproductologist, gynecologist, endocrinologist, MD, PhD. ; main specialty: gynecological endocrinology, treatment of infertility due to premature decline/insufficiency of ovarian function, treatment of embryo implantation disorders.
Obstetrician-gynecologist of the highest category, reproductive specialist. Main specialization: gynecological endocrinology — diagnosis and correction of conditions related to PCOS, premenstrual syndrome, ovarian-menstrual cycle disorders, endometriosis, correction of conditions related to different stages of menopause, ovarian cysts. Treatment of all forms of infertility and recurrent pregnancy loss.
Obstetrician-gynecologist, reproductive specialist. Main specialization: gynecology, infertility treatment, endocrine gynecology, pregnancy management (including pregnancy after IVF)
Obstetrician-gynecologist, reproductive specialist, ultrasound diagnostics expert. Main specialization: endocrine gynecology, management of high-risk pregnancies, diagnosis and treatment of all types of infertility, hysteroscopic treatment of uterine diseases